What is Rejuran (Salmon DNA) treatment in Korea?

March 27, 2026

Rejuran is one of the most talked-about skin regeneration treatments in Korea, often called the “salmon DNA treatment.” Many patients ask—what exactly is Rejuran and how does it work?



Below is a clear, SEO-friendly explanation.


What Is Rejuran (Salmon DNA) Treatment?
Rejuran is a
skin booster injection that uses PDRN (polydeoxyribonucleotide)—a purified DNA fragment derived from salmon.


Key concept:

• Injected into the dermis (skin layer)
• Uses
salmon DNA similar to human DNA
• Works to
repair and regenerate skin from within


👉 Simple summary:
Rejuran = skin healing & regeneration injection


How Rejuran Works (Mechanism)
Unlike fillers or Botox, Rejuran focuses on
cell-level repair.

What it does:

• Stimulates fibroblasts → increases collagen & elastin
• Repairs
damaged skin cells and barrier
• Reduces
inflammation and improves healing


👉 It doesn’t add volume—it restores skin health.


What Skin Problems It Treats
Rejuran is widely used in Korea for overall
skin quality improvement.

Common uses:

Fine lines and wrinkles
Acne scars and damaged skin
Enlarged pores and rough texture
Dull skin and loss of elasticity


👉 It’s a “foundation treatment” for healthier skin.


Results: Natural and Gradual Improvement
Rejuran works differently from instant treatments.


What to expect:

• Gradual improvement over 2–4 weeks
• Better skin texture, elasticity, and hydration
• More
natural, long-term results


👉 It’s often called a “slow aging” treatment.


Is Rejuran a Filler? (Important Difference)
Many people confuse Rejuran with fillers—but they are different.

Rejuran → repairs and regenerates skin
Fillers → add volume and shape


👉 Rejuran improves skin quality, not facial volume.


Treatment Process (What Happens During Procedure)

Typical session:

• Numbing cream applied (20–30 min)
• Multiple
micro-injections across the face
• Treatment time: ~15–30 minutes
• Small bumps (like mosquito bites) for 1–2 days


How Many Sessions Are Needed?

Typical plan:

3–4 sessions spaced 2–3 weeks apart
• Maintenance every
3–6 months


👉 Results build over time.


Why Rejuran Is So Popular in Korea

Korean dermatology focuses on skin quality, not just appearance.

Reasons for popularity:

• Works at cellular level, not just surface
• Safe for
sensitive and Asian skin types
• Fits the trend of
natural, regenerative treatments
• Often combined with lasers or boosters


Final Thoughts
Rejuran (salmon DNA treatment) is a
regenerative skin booster designed to heal, repair, and strengthen the skin from within.

Not a filler → no volume change
Focus = skin quality, texture, and long-term health
• Best for patients who want
natural, gradual improvement


If your goal is healthier, stronger skin rather than dramatic change, Rejuran is one of the most effective treatments in Korean dermatology.

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